QANDLI DIABETLI BEMORLARDA YUMSHOQ TO’QMALAR XIRURGIK INFEKSIYASINI DAVOLASH USULLARI

Abstract

Annotatsiya: Ushbu maqolada qandli diabet bilan og‘rigan bemorlarda yumshoq to‘qimalarning xirurgik infeksiyalari kechishining klinik-statistik tahlili bayon etilgan. Tadqiqot doirasida perioperativ giperglikemiya, tana massasi indeksi va tizimli yallig‘lanish javob sindromi (SIRS) o‘rtasidagi patogenetik bog‘liqliklar ikki qiyosiy guruh misolida o‘rganildi. Aniqlanishicha, barqaror yuqori glikemiya darajasi jarohat asoratlari xavfini 2.03 barobarga oshiruvchi hamda organizmda SIRS faolligini davomli ushlab turuvchi asosiy mustaqil omil hisoblanadi. Tana vazni ko‘rsatkichi mahalliy jarayonni og‘irlashtirsa-da, umumiy asoratlarda mustaqil xavf signali sifatida qayd etilmadi. Glikemik profilni qat’iy korreksiya qilish va jarohatlarni zamonaviy interaktiv bog‘lovlar bilan yuritish gospitalizatsiya muddatini sezilarli darajada qisqartirish imkonini beradi. Umuman olganda, ushbu toifadagi bemorlarni muvaffaqiyatli davolash xirurgik sanatsiya bilan birga tizimli metabolik o‘zgarishlarni intensiv nazorat qiluvchi ko‘p tarmoqli algoritmni talab etadi.Abstract. This scientific paper presents a clinical and statistical analysis of the course of surgical site soft tissue infections in patients with diabetes mellitus. Within the scope of the study, the pathogenic correlations between perioperative hyperglycemia, body mass index (BMI), and systemic inflammatory response syndrome (SIRS) were evaluated across two comparative groups. The findings indicate that a persistently elevated glycemic level serves as the primary independent risk factor, increasing the likelihood of wound complications by 2.03-fold and maintaining prolonged SIRS activity. Although body weight indices aggravated the localized presentation of the infection, they did not emerge as an independent prognostic risk factor (p = 0.79). Stringent correction of the glycemic profile combined with the management of wounds using modern interactive dressings allows for a significant reduction in hospitalization duration. Overall, successful treatment of this patient cohort necessitates a multidisciplinary algorithm that couples surgical debridement with intensive control of systemic metabolic disturbances.