DYNAMICS OF CHANGES IN IMPORTANT BIOCHEMICAL PARAMETERS IN PREECLAMPSIA

Authors

  • Sharipova Shakhnoza Ulugbekovna Author
  • Tuksanova Dilbar Ismatovna Author

Keywords:

. Preeclampsia is a serious pregnancy complication associated with multisystem pathological processes that pose significant risks to both the mother and fetus [1,3]. LDH is an indirect marker of tissue hypoxia and cellular injury, CRP is an important marker of systemic inflammation, while urea is a clinically relevant indicator of renal function. Assessment of their dynamic changes may help evaluate the progression of pathological processes in

Abstract

 Preeclampsia may be accompanied by metabolic and 
inflammatory changes resulting from systemic endothelial dysfunction and 
impaired microcirculation. This study investigated the dynamics of changes in 
important biochemical parameters, including lactate dehydrogenase (LDH), C
reactive protein (CRP), and urea, in women with preeclampsia. The results 
demonstrated that pathological changes in these parameters increased with the 
severity of preeclampsia. The identified changes reflect tissue hypoxia, 
systemic inflammatory response, and alterations in renal function and may be 
of significant importance for assessing and predicting the clinical course of 
preeclampsia.

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Published

2026-08-31

Issue

Vol. 10 No. 1 (2026): KELAJAK SARI YANGI O’ZBEKISTON: ILM-FAN, TEXNOLOGIYA VA TA’LIM

Section

Articles