DYNAMICS OF CHANGES IN IMPORTANT BIOCHEMICAL PARAMETERS IN PREECLAMPSIA

Abstract

Preeclampsia may be accompanied by metabolic and inflammatory changes resulting from systemic endothelial dysfunction and impaired microcirculation. This study investigated the dynamics of changes in important biochemical parameters, including lactate dehydrogenase (LDH), C-reactive protein (CRP), and urea, in women with preeclampsia. The results demonstrated that pathological changes in these parameters increased with the severity of preeclampsia. The identified changes reflect tissue hypoxia, systemic inflammatory response, and alterations in renal function and may be of significant importance for assessing and predicting the clinical course of preeclampsia