ASSOCIATION BETWEEN CONTINUOUS GLUCOSE MONITORING PARAMETERS AND FETAL HEMODYNAMICS IN PREGNANCIES COMPLICATED BY DIABETES MELLITUS

Abstract

Relevance. Pregnancies complicated by type 1 diabetes mellitus (T1DM), type 2 diabetes mellitus (T2DM), and gestational diabetes mellitus (GDM) are associated with an increased risk of adverse maternal and perinatal outcomes. Conventional assessment of glycemic control based on intermittent blood glucose measurements and glycated hemoglobin (HbA1c) may not fully reflect daily glucose fluctuations, postprandial hyperglycemia, nocturnal glucose abnormalities, and glycemic variability. Continuous glucose monitoring (CGM) provides detailed information on maternal glycemic patterns, including time in range (TIR), time above range (TAR), time below range (TBR), mean glucose, and coefficient of variation (CV). At the same time, fetal Doppler assessment allows non-invasive evaluation of fetoplacental and fetal circulation. The relationship between CGM-derived maternal glycemic patterns and fetal Doppler parameters in pregnancies complicated by different types of diabetes remains insufficiently investigated.